San Diego Commercial Real Estate

VIP Realty, we specialize in helping buyers, sellers, and tenants navigate the complexities of San Diego commercial real estate. Whether you're looking to purchase an income-producing asset, lease a high-visibility retail space, or sell your office building for top dollar, our team is here to help you succeed.

Commercial Real Estate - San Diego

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4540 Zion Avenue,

$11,800,000

4540 Zion Avenue,

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 250026591
10505 & 10509 San Diego Mission Road,

$7,500,000

10505 & 10509 San Diego Mission Road,

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 230018690
527-545 F Street,

$6,500,000

527-545 F Street,

0 Beds 7 Baths 0 SqFt Commercial Sale MLS® # 250021790
1068 Broadway, El Cajon

$6,000,000

↓ $250,000

1068 Broadway, El Cajon

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 250028048
5515 Market Street,

$5,999,000

5515 Market Street,

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 250018663
2201 Fletcher Pkwy, El Cajon

$4,950,000

↓ $249,000

2201 Fletcher Pkwy, El Cajon

0 Beds 1 Bath 0 SqFt Commercial Sale MLS® # 250035544
New
927-939 W Main Street, El Cajon

$4,900,000

927-939 W Main Street, El Cajon

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 250035724
New
960 S Santa Fe Ave, Vista

$4,400,000

960 S Santa Fe Ave, Vista

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 250041756
4870 Santa Monica Avenue,

$4,200,000

4870 Santa Monica Avenue,

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 250018765
2662 Garnet Avenue,

$4,200,000

2662 Garnet Avenue,

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 210026144
1045 14th Street,

$4,100,000

1045 14th Street,

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 250017399
N/A, Escondido

$4,000,000

N/A, Escondido

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 250029350
1350 Columbia St,

$3,875,000

↓ $325,000

1350 Columbia St,

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 250032382
N/A, Clairemont

$3,750,000

N/A, Clairemont

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 250030091
4647 University Ave,

$3,700,000

4647 University Ave,

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 240012514
New
110 Maple St,

$3,699,000

110 Maple St,

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 250033246
8911 La Mesa Boulevard, La Mesa

$3,600,000

8911 La Mesa Boulevard, La Mesa

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 200050546
New
4228 El Cajon Blvd,

$3,500,000

4228 El Cajon Blvd,

0 Beds 0 Baths 0 SqFt Commercial Sale MLS® # 250040445

San Diego is one of the most dynamic and desirable markets for commercial real estate in the United States. With a booming economy, diverse industries, world-class infrastructure, and year-round appeal, it’s no surprise that investors, business owners, and developers are turning their attention to this Southern California gem.

Why Invest in Commercial Real Estate in San Diego?

San Diego offers a unique blend of economic growth, quality of life, and industry diversity. The city is home to several booming sectors, including biotechnology, defense, education, healthcare, tourism, and clean energy. Combined with a strong population base and high barriers to entry for new development, San Diego commercial properties continue to see steady appreciation and investor demand.

Key benefits of investing in San Diego commercial real estate:

  • Strong Local Economy: Driven by the University of California San Diego (UCSD), a massive military presence, and a thriving startup culture.

  • High Demand & Limited Supply: Zoning and geography naturally limit available land, which helps support property values.

  • Premium Rent Growth: Commercial spaces in prime submarkets like Downtown, La Jolla, and Mission Valley consistently command premium rates.

  • Tax Benefits: Like other real estate investments, commercial properties in San Diego can offer depreciation and other tax incentives.

Types of Commercial Real Estate in San Diego

San Diego’s commercial real estate market is diverse and caters to a wide range of business needs and investment profiles. Here’s a breakdown of the most in-demand asset classes:

1. Office Space

From high-rise Class A office towers in Downtown San Diego to suburban flex spaces in Sorrento Valley, the office market offers great opportunities. Many businesses are reevaluating their workplace needs, leading to favorable conditions for tenants and savvy investors.

2. Retail Properties

San Diego is a popular shopping and tourism destination, which keeps retail spaces in demand. Neighborhood strip centers, standalone stores, and restaurant pads near beach communities and universities offer solid ROI potential, especially with mixed-use development trends gaining traction.

3. Industrial & Warehousing

Thanks to its strategic location near the U.S.–Mexico border and major ports, San Diego has become a hub for logistics and manufacturing. Otay Mesa and Miramar are hotspots for warehouse and industrial investments with strong tenant demand and low vacancy rates.

4. Multifamily & Mixed-Use

While multifamily falls into both commercial and residential categories, apartment buildings with 5+ units are considered commercial assets. San Diego’s housing demand makes multifamily an appealing long-term investment, especially in areas near transit lines and universities.

5. Medical & Life Science Facilities

With its reputation as a biotech and healthcare capital, San Diego has high demand for medical office buildings (MOBs), clinics, and lab space. UCSD, Scripps Health, and private sector leaders are fueling demand for innovative facilities.

6. Hospitality & Hotels

Tourism is a $10+ billion industry in San Diego. Properties near beaches, Gaslamp Quarter, and convention centers often generate high cap rates for experienced hospitality investors, though this sector can be cyclical.

Top Commercial Real Estate Markets in San Diego County

Each neighborhood and submarket within San Diego has its own commercial real estate character. Here are some of the top areas to consider:

Downtown San Diego

  • High-density office space, urban retail, and hospitality investments.

  • Attractive for law firms, tech companies, co-working spaces, and luxury hotels.

La Jolla / UTC

  • Premium office and medical real estate.

  • Ideal for biotech, research, and finance professionals.

Mission Valley

  • Central location with strong retail and mixed-use development growth.

  • Great for mid-sized businesses seeking visibility and accessibility.

Sorrento Valley & Torrey Pines

  • Major hub for life science, technology, and innovation.

  • Institutional-grade lab space and office campuses dominate this market.

Otay Mesa

  • Rapidly growing industrial zone with easy access to Mexico.

  • Excellent for warehousing, manufacturing, and logistics investments.

Chula Vista & South Bay

  • Fast-growing suburban market with residential and commercial demand.

  • A great spot for strip centers, small multifamily buildings, and medical offices.

San Diego Commercial Real Estate Services We Offer

At VIP Realty, we bring decades of experience and data-driven strategies to help you make confident commercial decisions in San Diego.

Buyer Representation

We help investors and business owners acquire commercial properties that match their financial goals and operational needs. From site selection to negotiation, we’ve got you covered.

Seller Representation

Looking to sell your commercial asset? Our expert marketing, valuation, and negotiation strategies ensure maximum exposure and top-dollar returns.

Tenant Representation

Searching for a new office, storefront, or industrial space? We help tenants secure favorable lease terms and navigate market conditions with confidence.

Landlord Representation

Our team works with property owners to attract and retain quality tenants, increase occupancy rates, and maximize property value through strategic leasing.

San Diego Commercial Real Estate Market Trends 

The commercial market in San Diego is showing signs of resilience and growth, even as other parts of the country remain uncertain. Key market trends include:

  • Adaptive Reuse Projects: Older buildings are being converted into modern offices, retail spaces, or mixed-use developments.

  • Increased Demand for Flex Space: Hybrid work models are driving demand for flexible layouts and short-term leases.

  • Green Building Focus: Sustainability is now a priority for both investors and tenants. Energy-efficient upgrades are boosting property appeal.

  • Institutional Capital Inflows: San Diego continues to attract REITs and private equity firms, particularly in life sciences and multifamily sectors.

Work with the Experts at VIP Realty

San Diego commercial real estate is competitive—but with the right strategy and expert guidance, it can also be highly rewarding. At VIP Realty, we don’t just open doors—we open opportunities. Our team combines deep local expertise with state-of-the-art marketing, negotiation, and investment tools to help our clients succeed in today’s complex commercial market.

Let’s Talk Commercial Real Estate in San Diego

Whether you’re looking to buy, sell, or lease commercial real estate in San Diego, VIP Realty is ready to help you reach your goals. Our team of experts will guide you every step of the way, from market research to closing and beyond.